Abstract Background Triple Negative Breast Cancer (TNBC) is a particular type of breast cancer with the highest mortality rate.Essential oils are concerned more and more as potential anti-cancer drugs.Methods TNBC cells were treated with different concentrations of navel orange peel essential oil (NOPEO), and then a variety of experiments Dishcloth
The Positivism Paradigm in Internal Audit Research: A Perspective of Contemporary Accounting Research
ABSTRACT This study aims to investigate the dominance of research with the paradigm of positivism in accounting, especially research related to the internal function of audit.The dominant paradigm in LED Visor accounting research to date is the positivist paradigm.In internal audit, all things are not only seen from the facts that are on the surfac
Safety and Efficacy of Palbociclib and Radiation Therapy in Patients With Metastatic Breast Cancer: Initial Results of a Novel Combination
Purpose: Palbociclib is a selective cyclin-dependent kinase 4/6 inhibitor approved for metastatic ER+/HER2- breast cancer.Preclinical evidence suggests a possible synergistic effect of palbociclib when combined with radiation therapy (RT); however, the toxicity of this pairing is unknown.We report preliminary results on the use of this combination.
c-Maf-positive spinal cord neurons are critical elements of a dorsal horn circuit for mechanical hypersensitivity in neuropathy
Summary: Corticospinal tract (CST) neurons innervate the deep spinal dorsal horn to sustain chronic neuropathic pain.The majority of neurons targeted by the CST are interneurons expressing the transcription factor c-Maf.Here, we used intersectional genetics to decipher the function of these Advanced Wound Care - Antimicrobials neurons in dorsal hor